Dados do Trabalho

Título

First report of Leishmania RNA virus 2 (LRV2) in Leishmania infantum strains from canine and human visceral leishmaniasis in the Southeast of Brazil

Introdução

Leishmania RNA virus 1 (LRV1) in South American Leishmania are commonly found in parasites belonging to the subgenus Viannia, while Leishmania RNA virus 2 (LRV2) were thought to be restricted to the Old-World pathogens of the subgenus Leishmania.

Objetivo (s)

In this work, we searched for LRV2 in strains of Leishmania (L.) infantum, the causative agent of visceral leishmaniasis (VL), from distinct hosts, clinical forms, and geographical origins.

Material e Métodos

Seventy-one isolates from Brazil and Honduras were examined for LRV2,

Resultados e Conclusão

and two, isolated from the canine (CUR268) and human (HP-EMO) cases in the southeastern of Brazil were positive for LRV2. To the best of our knowledge, this is the first detection of LRV2 in New World.

Palavras-chave

Leishmania; Leishmania infantum; leishmaniasis; Leishmania RNA virus, Totiviridae

Agradecimentos

FIOCRUZ, CNPq, FAPEMIG